Ethical Principles - 1049 Words

Henrietta Lacks, a woman that died of cervical cancer in 1951, single handedly changed the field of science. Not long before she passed away, a doctor took a sample of her cancer cells, the cells from her cervix were later on named HeLa cells, and these cells helped pave the way to numerous experiments and research all over the world. Even though HeLa brought along many achievements with its discovery, it also brought disappointments to some researchers, and pain for her family. You see, she nor her family consented to her cells being sampled, or the amounts of experiments and research that occurred after. Her family was never aware that such actions even took place. Even so, on February 1st, 1951, the day Henrietta Lacks walked in to John†¦show more content†¦Henrietta Lacks’ cervical tissue was taken without her consent, with no intentions of using them to benefit her in any way. In my opinion, all that were involved were in violation of the ethics code of conduct. Mary Kubicek and Dr. Gey, as well as the Dr. that allowed them to collect the sample were all in violation, simply because Henrietta Lacks did not consent to her tissue being used for cancer research. While Henrietta soon passed away from an aggressive form of cervical cancer, all others involved benefited from her cells. Her family knew nothing about the research, they knew nothing about her cells being collected, and it was not until 1976, when geneticists went looking for them (Films for the Humanities Sciences, 2012); believing that the cure to cancer was embedded in DNA. Dr. Gey, along with many other researchers, had been trying to grow human cells in vitro for many years. That was until Henrietta Lacks walked in to John Hopkins Hospital. Once HeLa cells were discovered, it made it possible for just about anything to be tested on them. As the HeLa cells continued to grow, so did the opportunity for many more experiments. During this time, the polio epidemic broke out; HeLa ce lls made it possible for the discovery of the polio vaccine. Leonard Hayflick, a Cell Biologist, had other plans in mind for cell line development. He established a cell line from the amnion of his daughter on theShow MoreRelatedThe Ethical Principles Of Respect For Autonomy984 Words   |  4 Pagesnurse to administer blood despite Mark’s refusal. This situation presents an ethical dilemma to the health professionals involved in Mark’s care. The ethical dilemma is whether to uphold his decision not to receive the blood and therefore risk his life or give him the blood to save his life despite knowing his religious status and beliefs. There are several ethical principles involved in this scenario. The ethical principles of respect for Autonomy, Beneficence, Non-maleficence, Veracity and FidelityRead MoreDomestic Surveillance And Ethical Principles1859 Words   |  8 PagesDomestic Surveillance and Ethical Principles Why do we neglect any ethical principles? According to the basics of utilitarianism, human deeds focus on common welfare. When we turn into spy’s and follow our family members, we hope that it will work in favor of our family welfare and common utility. We can compare home spying with domestic surveillance to show how ethical principles work in this area. â€Å"As a matter of fact, domestic surveillance focuses on potential crime prevention. On the other handRead MorePrinciples That Build The Foundation For Ethical Leadership761 Words   |  4 PagesThere are five principles that build the foundation for ethical leadership: respects others, serves others, shows justice, manifests honesty, and builds community (Northouse, 2016, p. 341). Treating others with respect means treating each person as if they are your goal, rather than just a means for a leader to achieve their goal (Northouse, 2016, p. 342). Respect also means allowing others to do what they do best; they are par t of the company for a reason, trying to pigeonhole them into doingRead MoreEthical Principles1475 Words   |  6 PagesAn Analysis of Ethical Principles in The Evaluation The term ‘ethical’, as I have come to apprehend it, is not just conforming to putative standards of conduct, but dealing with what is good or bad and with moral duty and obligation. Thomas A. Schwandt, a professor at the University of Illinois, notes that â€Å"while we can live in a world without standards and guidelines, we cannot live in a world without ethics.† Although, standards and guidelines have become prominent and are important guides inRead MoreEthical Principles3652 Words   |  15 PagesThe National Association for the Education of Young Children (NAEYC) is a nonprofit corporation dedicated to act on behalf of the interests of young children. The NAEYC Code of Ethical Conduct offers guidelines for responsible behavior and sets forth a common basis for resolving the principal ethical dilemmas encountered in early childhood care and education promoting a commitment to integrity, veracity, fairness, and human dignity at all levels; nevertheless, furth er research and/or developmentsRead MoreEthical Principles1161 Words   |  5 PagesEthical Principles Paper Nadia Brown University of Phoenix Ethical Principles Paper Henrietta Lacks was born on August 1, 1920, in Roanoke, Virginia and she died due to complications of cervical cancer on October 4, 1951.She had been receiving treatment at the Johns Hopkins Hospital in Baltimore, Maryland. At the hospital she was treated with radium tube inserts, which is said to be the standard treatment for cervical cancer in 1951. As a matter of routine, samples of her cervix were removedRead MoreThe Importance of Self-Awareness in Counselling2351 Words   |  10 PagesSaunders (2011). First Steps in Counselling. Ross-on-Wye: PCCS BOOKS. P36) Ethics can be defined as a set of moral principles or rules of conduct. Ethical principles and stand points play a major role in the decisions and angles that counsellors make and take in order to give the best possible help to a client. Counselling and psychotherapy practices are governed by a set of ethical principles developed by the British Association for Counselling and Psychotherapy (BACP). They are as follows: Fidelity:Read MoreEthical Principles, Decision And Principle1792 Words   |  8 PagesIn making ethical principles, decision and applying them in this case study scenarios; there are approaches to ethical analysis in addition to ethical systems and principles that will need to be considered especially where power and authority become the main issue and principle. John Rawls (1957) presented an abstract procedure for deciding moral issues. He stated that â€Å"moral principles can be developed through inductive logic which is through moral judgments such as common sense, open mind, personalRead MoreThe Diet Of A Baby Girl Named IIce1825 Words   |  8 Pages IIce was well nourished and was beginning to develop more than normally. However, IIce suffered from permanent neurological damage due to prematurity and malnutrition. Ethical Principles The ethical principles involved include: Autonomy, Finality, Justice, Non-maleficence, Utility, Tolerance and Rationality. These principles can be applied to the case as a whole or to specific events that unfolded. In respect to IIce, non-maleficence was violated when she was in the care of her parents. Her parentsRead MoreAn Ethical Framework And Ethical Principles3227 Words   |  13 Pagestreatment for the patient whilst adhering to the applicable legal and ethical frameworks imposed. In order to achieve this the assignment will commence by critically analysing how an ethical framework and ethical principles can and should be applied to both the above scenario and more generally in paramedic practice. From this understanding of the underlying principles the assignment will next examine both the legal and ethical standpoints surrounding capacity and consent and analyse how these should

The Stock Market Crash and The Great Depression in the US

Stock Market Crash 25 billion dollars lost in 1 day, roughly 25% of the nations population was without a job, and the suicide rate skyrocketed. These are just a few factors that turned the Stock Market Crash of 1929 into the Great Depression, one of the longest and worst economic downturns of that time, according to History.com. 16 million shares were lost at the New York Stock Exchange, eliminating thousands of investors on October 29th, 1929. The Stock Market Crash impacted the United States by putting Millions of people out of jobs, and putting America in one of the deepest financial and economical holes of that time. Today, Americans are still worried it could happen again, which is causing some people to not trust banks, or†¦show more content†¦The â€Å"Bear Market† is a market that seems to be in a long term decline, this occurs when the economy enters a recession. The â€Å"Bull Market† is when the market seems to be in a long-term incline. Therefore the stock prices wil l continue to rise to high numbers. On Thursday October 24th, 1929; Richard Whitney, who was the vice-president of the New York Stock Exchange and the broker for the House of Morgan made an attempt to calm things down. Brokers with more money got together, and bought stock above the current market. It worked for quite some time, but on Tuesday October 29th, the stock market fell apart. The value of stocks declined rapidly, and money was lost almost instantly. The Ignorance caused lots of panicking and unneeded stress. People started to get worried, and this lead into the â€Å"Great Depression† of 1929. This financial breakdown affected every aspect of life as an American. Those hurting during the â€Å"Great Depression† were more surprised and shocked than mad. Many Americans sank into deep depression because they were unable to find jobs, therefore they could not support their families. 7 to 8 percent of the population owned stocks. John Jakob Raskob, a rich industr ialist spoke about how easy it was for americans to become rich, All you had to do was invest in stocks. The Federal Reserve System did pretty much nothing to keep track of how much money someone could take out, and use for aShow MoreRelatedThe Stock Market Crash Of 19291590 Words   |  7 PagesThe cause of the crash in the stock market in 1929, was an incident that occurred on October 29, which was called Black Tuesday. Investors traded 16 million dollar of shares toward the New York Stock Exchange in a day, upon that billions of dollars were lost and investors lost their business or their jobs. one of the major reason why was that car and other factory produced certain quota of cars. during the great depression people who were rich is now poor and the poor and the poorer. people wereRead MoreJim Braddock and The Great Depression1154 Words   |  5 PagesFranklin Roosevelt said, â€Å"When you come to the end of your rope, tie a knot and hang on,† and it directly relates to the Great Depression. People thought that because of this huge downturn that they would not survive but they had to â€Å"tie a knot in their rope,† and continue to try and survive. The great depression was a time of horror and failure. The giant Stock Market crashes of the 1930’s triggered this major blow to the nations economy. This major devastation also leads many families intoRead MoreThe Great Depression Essay1390 Words   |  6 PagesIntroduction: The world had faced two main economic problems. The first one was the Great Depression in the early of 20th Century. The second was the recent international financial crisis in 2008. The United States and Europe suffered severely for a long time from the great depression. The great depression was a great step and changed completely the economic policy making and the economic thoughts. It was not only an economic situation bit it was also miserable making, made people more attentionRead MoreThe Great Depression By Franklin D. Roosevelt s New Deal Legislation1115 Words   |  5 PagesWhat do you think about when you hear The Great Depression? Some might say the worst economic time in the United States of America. The Great Depression was one of the longest and innermost economic downturn in the world of history between the years of 1929 and 1939. Also, The Great Depression led to the Federal Government having a more involved role in America s economy, this was done through the creatio n of Franklin D. Roosevelt s New Deal Legislation, which turned out to be effective becauseRead MoreWill Mcclellan3/5/17. Herbert Hoover. Herbert Herbert Is874 Words   |  4 Pagestimes such as the stock market crash of 1929 and the Great Depression. These were tough tasks for a president and since the Great Depression lasted so long, I don’t believe that he handled them very well so I believe that Herbert Hoover belongs in the hall of shame. Hoover became President in March, 1929. The stock market crash occurred in October, 1929 and lasted for four days. The stock market lost more than 25% of its value over those four days and is considered the worst crash in the historyRead MoreThe Crisis Of The 1929 Stock Market Crash1378 Words   |  6 PagesJuly 2007, the United States were kicked off by the subprime mortgage crisis, emphasized by the banking and financial crisis of 2008. The global economic crisis called the Great Recession followed in 2008. It has been famously regarded as preventable by the memory of the Great Depression in the late twenties. The stock market crash of â€Å"Black Thursday† on the 24th of October 1929 marked the end of the â€Å"Roaring Twenties†, temporary period of prosperity and endless hope in the United States. But this hopeRead MoreGreat Depression And The Great Recession864 Words   |  4 PagesThe â€Å"Great Depression† and the â€Å"Great Recession† are two of the darkest times in American history. There is much debate about the cause of the Great Depression and how it differed from the cause of the Great Recession. Many people believe that the stock market crash of 1929 played a major role the Great Depression. On the other hand, the stock market crash of 2008 drove America into the Great Recession. The causes of stock market crashes are often unforeseen, but many have detectable indicators.Read MoreThe Great Depression : The Fall Of A Nation1701 Words   |  7 PagesThe Great Depression: The Fall of a Nation The Great Depression was a hard time for America. The name fits like a glove because it was, in fact a depression. The Great Depression was crucial to American history because it changed every aspect of American life, revealed how big a power America was, and it established multiple government agencies around the world to make sure something like it never happens again. The economy was at a highpoint in 1929. It was easier for people to buy stock (â€Å"StockRead MoreThe Stock Market Crash of 19291289 Words   |  6 Pagesat home or in the bank into the stock market. People migrated to the prosperous cities with the hopes of finding much better life. In the 1920s, the stock market reputation did not appear to be a risky investment, until 1929.First noticeable in 1925, the stock market prices began to rise as more people invested their money. During 1925 and 1926, the stock prices vacillated but in 1927, it had an upward trend. The stock market boom had started by 1928. The stock market was no longer a long-term investmentRead MorePresident Herbert Hoover : The Legacy Of The Great Depression1156 Words   |  5 PagesHoover’s lack of action that brought America to its knees before the Great Depression. Should Herbert Hoover be defined as the ineffective president accountable for the aftermath of the Stock Market Crash of 1929 or did he ac tually play an important role in alleviating the economic turmoil, but simply went unrecognized for his heroic contributions? Although he is known to be an excellent businessman, the prevention of the Stock Market Crash of 1929 was an impossible feat for even someone as educated as

Business Stakeholders Knowledge Management System

Question: Discuss about the Report for Business Stakeholders of Knowledge Management System. Answer: Stakeholder refers to any person that has interest in the proposed information or knowledge management system. It is extremely important to research on the stakeholder requirement for these systems to understand the stake of the various technical and non-technical workers and also to determine the influence of the stakeholder on the activities associated with the project. Assignment of roles and responsibilities can also be efficiently done only after understanding the stakeholder requirement (Pouloudi, 2016). There are a number of methods to collect information from the stakeholders that include one-on-one discussions with the stakeholder, group discussions, and conduction of collaborative workshops along with conference calls and surveys. It is suggested to record the outcomes of any of these methods in a formal manner (Abudi, 2010). Stakeholder management and assessment is an important activity in a project and the steps in providing information to the external stakeholders should be managed well. The main objectives of the system are: To provide the information to the external stakeholders without compromising on the information confidentiality, integrity and security. To provide the information to the external stakeholders as per the project schedule The following strategy must be followed while training the external users: A training plan must be developed and shared with the trainer and the trainees before the training. Resources necessary for the training that is a facilitator, trainer or group of trainers and trainees willing to attend the training must be identified. Method of training shall be finalized on mutual consent. For a web based training, audio/video conferencing details along with the schedule must be shared with all the members and in case of an in-person training session, venue details must be shared and booked in advance. The documents that will be followed during the training must be circulated in advance. The success of the training activity can be judged on the basis of the feedback form comprising of a list of questions about the training material, schedule, trainer interaction level and likewise. The form must be filled and sent back to the facilitator by all the trainees. The system can be promoted to the external users by arranging the introductory and training sessions for them that will provide a brief on the features of the same and the steps to use the same. User manuals and guides highlighting the advanced features and benefits must also be circulated. The system integrity while providing access to external users can be maintained by following strict access control measures along with the user authentication and authorization methods. Also, the information and data present on the system must be encrypted to avoid any security risks. An automated sales management information system must be installed to keep the sales information maintained and secure at the same time. In case of the loss of sales report from the customer management system, the back-end team must be contacted for assistance to provide the same from the back-up and recovery database. To avoid the data loss in case of a crash, effective back-up strategies must be adopted along with the disaster recovery for recovering the data as and when required. Customer Relationship Management (CRM) software must be used by the organization to improve customer interaction and associated activities. In case of erroneous information sent to the supplier, the information must be reverted and replaced with the corrected piece of the same. Order processing and inventory control systems must be installed to streamline the orders that are received from the customers and to avoid the issues of shipment delays and backorders. Transaction Processing Information Systems are the systems which are used to manage the transactions at the operational level. These systems perform the task of validating, sorting, listing, merging, calculating and updating the information to provide detailed reports and lists. Some of the examples of transaction processing information systems include payroll systems, order processing systems, stock control systems and reservation systems (Al-Mamary, Shamsuddin, Aziati, 2016). Strengths: These systems can handle several thousand transactions simultaneously without causing errors which is otherwise not possible through manual operations. This leads to saving of a lot of time and effort. These systems also enable the customers from all across the globe to access a system at any time as these are always available. Weaknesses The biggest weakness of these systems is the security threats that these are exposed to. There is also hardware and network requirement that needs to be fulfilled to implement and use these systems. The maintenance that these systems ask for also adds to the weakness of the transaction processing systems (Fitzpatrick, 2016). SWOT Analysis stands for the determination of an organizations strengths, weaknesses, opportunities and threats. It is a strategic planning tool for the organization to understand the internal (strengths and weaknesses) and external (opportunities and threats) factors that may affect the performance. SWOT Analysis can be used to determine the effectiveness of an information management system as it can easily evaluate the success or failure of the same. It also gives information on the features that distinguish the system from the rest which make it distinguished from the competitors (Chand, 2014). The information system that has been chosen for assessment is the Transaction Processing System. The system has been found to be extremely effective and usable for the employees to perform operational transactions. It has also emerged as an essential component in the information systems that are installed in the organization. The assessment procedure that was followed to come up to the conclusion stated above is described as follows: A monitoring and evaluation plan was designed to perform the assessment of the system Monitoring of the system was done by collecting the information through on-site visits, review of the data and examination of the reports. Data was collected in the form of reports, records, indicators and formats Evaluation to assess the performance was done by determining the achievements, impact, cost effectiveness and sustainability of the system (www.pathfinder.org, 2016). The major drawbacks that were received while assessing the transaction processing information systems were in terms of the security. Security threats and risks are on an ever increasing pace in the world of information systems and the same has impacted the transaction processing systems as well. The same can be approved by using stronger security mechanisms such as improved access control, use of latest anti-virus and internet security along with the installation of firewalls in the system. Other employees that were involved in assessing the system and suggesting the improvements were the network engineers that determined the network security attacks affecting the system, internal and external users that use the system and the maintenance staff that provides assistance and support. Assessment Report Objective The objective of the report is to analyze the effectiveness and performance of transaction processing information system in the organization. Stakeholders The stakeholders that are involved during the assessment of the system are the system engineers, network engineers, maintenance team and end-users. Assessment Procedure A checking and assessment arrangement was intended to play out the evaluation of the framework Checking of the framework was finished by gathering the data through on location visits, audit of the information and examination of the reports Information was gathered as reports, records, markers and configurations Assessment to evaluate the execution was finished by deciding the accomplishments, sway, cost viability and maintainability of the framework Assessment Result The system has been observed to be to a great degree compelling and usable for the workers to perform operational exchanges. It has additionally risen as a key part in the data systems that are introduced in the association. Recommendations The real disadvantages that were gotten while evaluating the transaction processing data systems were as far as the security. Security dangers and dangers are on a perpetually expanding pace in the realm of data systems and the same has affected the transaction processing systems too. The same can be endorsed by utilizing more grounded security instruments, for example, enhanced access control, utilization of most recent tools against viruses and web attacks alongside the establishment of firewalls in the system. References Abudi, G. (2010). Best Practices for Gathering Requirements from Your Stakeholders - Gina Abudi. Gina Abudi. Retrieved 4 August 2016, from https://www.ginaabudi.com/best-practices-for-gathering-requirements-from-your-stakeholders/ Al-Mamary, Y., Shamsuddin, A., Aziati, N. (2016). The Role of Different Types of Information Systems In Business Organizations : A Review. Retrieved 4 August 2016, from https://paul-hadrien.info/The%20Role%20of%20Different%20Types%20of%20Information.pdf Chand, S. (2014). SWOT Analysis: Meaning and Importance of SWOT Analysis | Management. YourArticleLibrary.com: The Next Generation Library. Retrieved 4 August 2016, from https://www.yourarticlelibrary.com/management/swot-analysis-meaning-and-importance-of-swot-analysis-management/25826/ Fitzpatrick, M. Fitzpatrick, M. (2016). The Advantage Disadvantage of Transaction Processing Systems | eHow. eHow. Retrieved 4 August 2016, from https://www.ehow.com/info_8708023_advantage-disadvantage-transaction-processing-systems.html Pouloudi, A. (2016). Aspects of the Stakeholder Concept and their Implications for Information Systems Development. Retrieved 4 August 2016, from https://www.computer.org/csdl/proceedings/hicss/1999/0001/07/00017030.pdf www.pathfinder.org,. (2016). Monitoring and Evaluation and Management Information Systems (MIS). Retrieved 4 August 2016, from https://www.pathfinder.org/publications-tools/pdfs/Strengthening-You-Organization-A-Series-of-Modules-and-Reference-Materials-for-NGO-and-CBO-Managers-and-Policy-Makers-Monitoring-and-Evaluation-and-MIS.pdf

Learning Chapters on Project Procurement Management Essay Example

Learning Chapters on Project Procurement Management Paper After reading this chapter, you will b understand the Importance of prop Increasing use of outsourcing for info Describe the work involved in planning determining the proper type of contract t management plan, statement of work, so buy analysis Discuss what is involved in conducting obtaining seller responses, selects Understand the process of admit meet relationships and monitor Describe the process of closing Discuss types of software avail management Marie McBride could not believe how much money her company was paying for outside consultants to help the company finish an important operating system conversion project. The consulting companys proposal said it would provide experienced professionals who had completed similar conversions, and that the Job would be finished in six months or less with four consultants working full time. Nine months later her company was still paying high consulting fees, and half of the original consultants on the project had been replaced with new people. One new consultant had graduated from college only two months before and had extremely poor communications skills. Marries internal staff complained that they were wasting time training some of these experienced professionals. Marie talked to her companys purchasing manager about the contract, fees, and special clauses that might be relevant to the problems they were experiencing. Marie was dismayed at how difficult it was to interpret the contract. It was very long and obviously written by someone with a legal background. We will write a custom essay sample on Learning Chapters on Project Procurement Management specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Learning Chapters on Project Procurement Management specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Learning Chapters on Project Procurement Management specifically for you FOR ONLY $16.38 $13.9/page Hire Writer When she asked what her company could do since the consulting firm was not following Its proposal, the purchasing manager stated that the proposal was not part of the official contract. Marries company was paying for time and materials, not specific deliverables. There was no clause stating the minimum experience level required for the consultants, nor were there penalty clauses for not completing the work on time. There was a termination clause, however, meaning the company could terminate the contract. Marble wondered why her company had signed such a poor contract. Was there a better way to deal with procuring services from outside the company? Although global outsourcing displaces some IT workers, total employment In the united States increases, according to IOTA, as the benefits ripple through the economy. I en Incremental economic actual TTY Tanat Tools outscore II outsourcing creates over 257,000 net new Jobs in 2005 and is expected to create over 337,000 net new Jobs by 462 P oliticians debate on whether offshore outsourcing helps their own country or not. Andy Boor, chief operating officer of a computer network support service provider, describes outsourcing as an essential part of a healthy business diet. He describes good vs.. Bad outsourcing as something like good vs.. Bad cholesterol. He says that most people view offshore outsourcing as being bad because it takes Jobs away from domestic workers. However, many companies are realizing that they can use offshore outsourcing and create more Jobs at home. For example, Atlanta-based Delta Air Lines created 1,000 call-center Jobs in India in 2003, saving $25 million, which enabled it to add 1,200 Job positions for reservations and sales agents in the United States. 2 Other companies, like Wall-Mart, successfully manage the majority of their information technology projects in-house with very little commercial software and no outsourcing at all. (See the Suggested Reading on the companion Web site on Wall- Marts Way. ) Deciding whether to outsource, what to outsource, and how to outsource are important topics for many organizations throughout the world. In a 2008 survey, 74 percent of 600 global procurement executives believed that procurement issues are a high priority for their companies. About half of respondents also said that their companies focus too much on cost reduction instead of value creation. They also believe they are missing opportunities by not focusing on using technology to improve procurement processes. For example, 72 percent of respondents have less than 10 percent of their spend channeled through procurement and sourcing applications. 3 Most organizations use some form of outsourcing to meet their information technology needs, spending most money within their own country. A 2008 report on IT outsourcing trends in the U. S. And Canada revealed the following: Application development is the most popular form of IT outsourcing and was used by 53 percent of organizations surveyed. Of the surveyed organizations, 44 percent outsourced application maintenance, 40 percent outsourced Web site or e-commerce systems, and 37 percent outsourced disaster recovery services. The IT function with the largest percentage of work outsourced is assister recovery services, accounting for 50 percent of total IT outsourcing. Mortifications see the benefit in having an outside party perform offset storage or maintenance of a recovery facility. Desktop support is the second most outsourced IT function (48 percent), followed closely by data center operations and help desk (47 percent each) and Web site or e-commerce systems (46 percent). IT security is at the bottom of the list, with only 29 percent of the work being outsourced. Even though application development and maintenance are frequently outsourced, they are a low percentage of the amount of total IT work outsourced. Application development and maintenance are often outsourced selectively since most organizations choose to do many projects in-house. 4 Procurement means acquiring goods and/or services from an outside source. The term procurement is Widely used in government; many private companies use the terms purchasing and outsourcing. Organizations or individuals who provide procurement services are referred to as suppliers, vendors, contractors, subcontractors, or sellers, with suppliers being the most widely used term. Many information technology projects involve the use of goods and services from outside he organization. As described in Chapter 2, outsourcing has become a hot topic for research and debate, especially the implication of outsourcing to other countries, referred to as offspring. The outsourcing statistics below are from an Information Technology Association of America (IOTA)-sponsored report: Spending for global sources of computer software and services is expected to grow at a compound annual rate of about 20 percent, increasing from about $1 5 billion in 2005 to $38 billion in 2010. Total savings from offshore resources diddling the same time period are estimated to grow from $8. Billion to $20. 4 billion. The cost savings and use of offshore resources lower inflation, increase productivity, and lower interest rates, which boosts business and consumer spending and increases economic activity. Chapter 12 Project Procurement Management Because outsourcing is a growing area, it is important for project managers to understand project procurement management. Many organizations are turning to outsourcing to: Reduce betrothed and recurrent costs. Outsourcing suppliers are often able to use economies of scale that may not be available to the client alone, especially for hardware and software. It can also be less expensive to outsource some labor costs to other organizations in the same country or offshore. Companies can also use outsourcing to reduce labor costs on projects by avoiding the costs of hiring, firing, and reassigning people to projects or paying their salaries when they are between projects. Allow the client organization to focus on its core business. Most organizations are not in business to provide information technology services, yet many have spent valuable time and resources on information technology functions when they should have focused on core competencies such as marketing, customer arrive, and new product design. By outsourcing many information technology functions, employees can focus on Jobs that are critical to the success of the organization. Access skills and technologies. Organizations can gain access to specific skills and technologies when they are required by using outside resources. For example, a project may require an expert in a particular field or require the use of expensive hardware or software for one particular month on a project. Planning for this procurement ensure that the needed skills or technology will be available for the project. Provide flexibility. Outsourcing to provide extra staff during periods of peak workloads can be much more economical than trying to staff entire projects with internal resources. Many companies cite quicker flexibility in staffing as a key reason for outsourcing. Increase accountability. A well-written contract-a mutually binding agreement that obligates the seller to provide the specified products or services and obligates the buyer to pay for them-can clarify responsibilities and sharpen focus on key deliverables of a project. Because contracts are legally binding, there is more accountability for delivering the work as stated in the contract. In December 2002, who organ Chase announced a sieving to MOM, both companies en- year, $5 billion deal too bragged that the contract w TTS med like a win-win situational would make money an gang Chase could push for innovation. The contract less than two years However, in September 200 egger fit with Comparing Chaises busting its existence because the pro news strategy. According to Austin rumination officer at Comparing Chi couture is best for the long-term gar We believe managing our own techno and success of our company as well a railroaders. However, IBM said he can contract was simply a result of Comparing Chaises merger earlier that year with Bank It tried to shrug off the loss of a large business deal. The combined firm found its an abundance of IT assets, IBM spokesperson James Icicles said. This decision w other business decisions related to the merger. 6 Outsourcing can also cause problems in other areas for companies and nations as a whole. For example, many people in Aus tralia are concerned about outsourcing software development. The Australian Computer Society says sending work offshore may lower ten under AT students entering II courses, deplete ten mummer AT Skilled IT professionals, and diminish the nations strategic technology capability. Another issue is security, which encompasses the protection of intellectual property, integrity of data, and the reliability of infrastructure in offshore locations. 7 The success of many information technology projects that use outside resources is often due to good project procurement management. Project procurement management includes the processes required to acquire goods and services for a project from outside the performing organization. Organizations can be either the buyer or the seller of products or services under a contract. There are four main processes in project procurement management: Organizations must also consider reasons they might not want to outsource. When an organization outsource work, it often does not have as much monitor over those aspects of projects that suppliers carry out. In addition, an organization could become too dependent on particular suppliers. If those suppliers went out of business or lost key personnel, it could cause great damage to a project. Organizations must also be careful to protect strategic information that could become vulnerable in the hands of suppliers. According to Scott McNealy, CEO of Sun Microsystems, Inc. , What you want to handle in-house is the stuff that gives you an edge over your competition-your core competencies. I call it your secret sauce. If youre on Wall Street and you have your own program for tracking and analyzing the market, youll hang onto that. At Sun, we have a complex program for testing microprocessor designs, and well keep it. 5 Project teams must think carefully about procurement issues and make wise decisions based on the unique needs of their projects and organizations. They can also change their minds on outsourcing as business conditions change. . 3. Planning procurements involves determining what to procure, when, and how. In procurement planning, one must decide what to outsource, determine the type of contract, and describe the work for potential sellers. Sellers are contractors, suppliers, or providers who provide goods and services to other organizations. Outputs of this process include a procurement management plan, statements of work, make-or-buy decisions, procurement documents, source selection criteria, and change requests. Conducting procurements involves obtaining seller responses, selecting sellers, and awarding contracts. Outputs include selected sellers, procurement contract awards, resource calendars, change requests, and updates to the project management plan and other project documents. Administering procurements involves managing relationships with sellers, monitoring contract performance, and malting changes as needed. The main outputs of this process Include procurement documents talon, organizational 4. Process asset updates, change requests, and project management plan updates. Closing procurements involves completion and settlement of each contract, including resolution of any open items. Outputs include closed procurements and organizational process asset updates. Figure 12-1 summarizes these processes and outputs, showing when they occur in a typical project. Planning Process: Plan procurements Outputs: Procurement management plan, procurement statements of work, make-or-buy decisions, procurement documents, source selection criteria, and change requests 466 Executing Process: Conduct procurements Outputs: Selected sellers, procurement contract award, resource calendars, change requests, project management plan updates, project document updates Monitoring and Controlling Process: Administer procurements Outputs: Procurement communication, organizational process asset updates, change requests, project management plan updates Closing Process: Close procurements Outputs: Closed procurements, organizational process asset updates Project Start Project Finish FIGURE 121 Project procurement management summary The Boots Company PLY, a Nottingham, England, outsourced its information t Tiber 2002. The Boots Company signed a ten-year d expected to save $203. 9 million over that period com systems itself. IBM managed and developed The Boots Comma cou ture from the mainframes to the tills in our 1,400 stores, to the co , said spokesperson Francis Thomas. More than 400 Boots employees we Vims payroll but continued to work at Boots head office, with extra IBM s n as needed. Thomas added, The great thing about this is that if IBM has an expert in Singapore and [if} we need that expertise, we can tap Into It Tort tender months. It Keeps our costs on an even Keel. 8 is not uncommon moon for long contracts to be renegotiated, becoming either shorter or longer in length. May 2006, Boots and IBM began discussing amendments to their contract because m of Boots IT infrastructure renewal program (including a new pharmacy system and roll) was complete. A Boots spokesman said that the many achieved its goal much quicker than planned. In contrast, in 2005 Boots renegotiated its EYE million, seven-yea IT contract it initially signed in 2002 with Sans, extending it for another two years to 2011 in a EYE million deal. 9 It is also not uncommon to take advantage of competition the changing marketplace for major procurements. In 2008, Boots announced that I have up to six different suppliers competing to supply its IT products and services ova next year. The company is keeping its business system management team and service management in-house? including helpless and project management. 10 Properly planning purchases and acquisitions and writing good contracts can also save organizations millions of dollars. Many companies centralize purchasing for products, such as personal computers, software, and printers, to earn special pricing discounts. For example, in the mid-asses the U. S. Air Force awarded a five-year, multimillion-dollar contract to automate 15 Air Force Systems Command bases. The project manager and contracting officer decided to allow for a unit pricing strategy for some items required in the contract, such as the workstations and printers. By not requiring everything to be negotiated at a fixed cost, the winning supplier lowered its final bid y more than $40 million. II Planning procurements involves identifying which project needs can best be met by using products or services outside the organization. It involves deciding whether to procure, how to procure, what to procure, how much to procure, and when to procure. An important output of this process is the make-or-buy decision. A make-or- buy decision is one in which an organization decides if it is in its best interests to make certain products or perform certain services inside the organization, or if it is better to buy them from an outside organization. If there is no need to buy any reduces or services from outside the organization, then there is no need to perform any of the other procurement management processes. For many projects, properly outsourcing some information technology functions can be a great investment, as shown in the following examples of What Went Right. Inputs needed for planning procurements include the scope baseline, requirements documentation, teaming agreements, the risk register, risk-related contract decisions, activity resource requirements, the project schedule, activity cost estimates, the cost performance baseline, enterprise environmental factors, and organizational process assets. For example, a large clothing company might consider outsourcing the delivery of, maintenance of, and basic user training and support for laptops supplied to its international sales and marketing force. If there were suppliers who could provide this service well at a reasonable price, it would make sense to outsource, because this could reduce fixed and recurring costs for the clothing company and let them focus on their core business of selling clothes. It is important to understand why a company would want to procure goods or services Ana want Inputs are anemia to plan purchases and acquisitions. In the opening case, Marries company hired outside consultants to help complete an operating system conversion project because it needed people with specialized skills for a short period of time. This is a common occurrence in many information technology projects. It can be more effective to hire skilled consultants to perform specific tasks for a short period of time than to hire or keep employees on staff full time. However, it is also important to define clearly the scope of the project, the products, services, or results required, market conditions, and constraints and assumptions. In Marries case, the scope of the reject and services required were relatively clear, but her company may not have adequately discussed or documented the market conditions or constraints and assumptions involved in using the outside consultants. Were there many companies that provided consultants to do operating conversion projects similar to theirs? Did the project team investigate the background of the company that provided the consultants? Did they list important constraints and assumptions for using the consultants, such as limiting the time that the consultants had to complete the conversion project or the minimum years of experience for any consultant assigned o the project? It is very important to answer these types of questions before going into an outsourcing agreement. Dividing both sides by $400, you get: which means that the purchase cost equals the lease cost in 30 days. So, if you need the equipment for less than 30 days, it would be more economical to lease it. If you need the equipment for more than 30 days, you should purchase it. In general, leasing is often cheaper for meeting short-term needs, but more expensive for long- term needs. Expert Judgment Tools and Techniques for Planning Procurements There are several tools and techniques to help project managers and their teams in landing procurements, including make-or-buy analysis, expert Judgment, and contract types. Make-or-Buy Analysis Make-or-buy analysis is a general management technique used to determine whether an organization should make or perform a particular product or service inside the organization or buy from someone else. This form of analysis involves estimating the internal costs of providing a product or service and comparing that estimate to the cost of outsourcing. Consider a company that has 1,000 international salespeople with laptops. Using make-or-buy analysis, the company would compare en cost AT provoking tense services using Internal resources to ten cost AT Dulling those services from an outside source. If supplier quotes were less than its internal estimates, the company should definitely consider outsourcing the training and user support services. Another common make-or-buy decision, though more complex, is whether a company should develop an application itself or purchase software from an outside source and customize it to the companys needs. Many organizations also use make-or-buy analysis to decide if they should either purchase or lease items for a particular project. For example, suppose you need a piece of equipment for a project that has a purchase price of $12,000. Assume it also had a daily operational cost of $400. Suppose you could lease the same piece of equipment for $800 per day, including the operational costs. You can set up an equation in which the purchase cost equals the lease cost to determine when it makes sense financially to lease or buy the equipment. In this example, d = the number of days you need the piece of equipment. The equation would then be: Experts inside an organization and outside an organization could provide excellent advice in planning purchases and acquisitions. Project teams often need to consult experts within their organization as part of good business practice. Internal experts might suggest that the company in the above example could not provide quality training and user support for the 1,000 laptop users since the service involves so many people with different skill levels in so many different locations. Experts in the company might also know that most of their competitors outsource this type of work and know who the qualified outside suppliers are. It is also important to consult legal experts since contracts for outsourced work are legal agreements. Experts outside the company, including potential suppliers themselves, can also provide expert judgment. For example, suppliers might suggest an option for salespeople to purchase the laptops themselves at a reduced cost. This option would solve problems during employee turnover-exiting employees would own their laptops and new employees would purchase a laptop through the program. An internal expert might then suggest that employees receive a technology bonus to help offset what they might view as an added expense. Expert Judgment, both internal and external, is an asset in making many procurement decisions. Types of Contracts $80th = $12,000 + $40th Subtracting $40th from both sides, you get: $40th = $12,000 Contract type is an important consideration. Different types of contracts can be used in different situations. Three broad categories of contracts are fixed price or lump sum, cost reimbursable, and time and material. A single contract can actually include all three of these categories, if it makes sense for that particular procurement. For example, you could have a contract with a seller that includes purchasing specific hardware for a fixed price or lump sum, some services that are provided on a cost lampshades Dados, Ana-eaten services Tanat are approver on a tale Ana material basis. Project managers and their teams must understand and decide which approaches to use to meet their particular project needs. It is also important to understand when and how you can take advantage of unit pricing in contracts. Fixed- price or lump-sum contracts involve a fixed total price for a well-defined product or service. The buyer incurs little risk in this situation since the price is predetermined. The sellers often pad their estimate somewhat to reduce their risk, realizing their rice must still be competitive. For example, a company could award a fixed-price contract to purchase 100 laser printers with a certain print resolution and print speed to be delivered to one location within two months.

Formwork System Example

Formwork System Example Formwork System – Article Example Introduction Cases of concrete structures collapsing while under construction have been taking place ever since concrete started being put in formwork. Causes and cases of such kind of structural failures have been recorded as well as documented in several journals, articles and texts. This report will focus on collapse of a 16 storey building that took place on 25th of January 1971 at 2000 Commonwealth Avenue in Boston, MA (Nawy, 2008).The project-The apartment structure was made up of cast-in-place with a reinforced concrete level slab having a middle elevator shaft. Generally this sort of construction is common with buildings having multi-stories since they only need a minimal slab width which lessens the general elevation of the building. The 2000 Commonwealth Avenue building had a design of 16 stories inclusive of a mechanical room on top of a 5-foot crawl space on its roof. In addition, the building also comprised of 2 levels of basement parking. The first floor comprised of an cillary spaces, swimming pool together with one apartment, whereas the 2nd up to 16th floor had 132 apartments (Nawy, 2008).Type of form/structure-The method used in construction was that of a level plate waffle slab having solid slabs at its column caps. This was actually the very first time motorized buggies were used in pouring of such a structure as this. Thus the collapsed floor was the 1st one above grade propped up on 2 tiers of shores totaling 22’ high. The weight of the buggies was 3000 lb loaded having been run at 12mph.There was a total of 8 buggies when the structure failed with approximately 500 cubic yards of concrete having been placed already. Investigations later laid the blame exclusively on insufficient prerequisites in the formwork to defy lateral forces.Cause of failureThe failure was due to the following problems; engineers’ structural specifications were not followed, there was no concrete design strength as well as shoring and if present, it was removed quickly. In addition, reinforcement was improperly placed, minimal control of construction site, lack of engineering or architectural inspection done and finally the city of Boston did not provide adequate inspection (Nawy, 2008).Consequences-The collapse resulted in the death of 4 workers and 20 others injured. There was also destruction and loss of building materials and other resources.In conclusion, several lessons can be learnt from this failure such as the importance of adhering to building controls at every stage of construction. If adequate measures were implemented to ensure that original and proper design was followed, failure would not have taken place (Nawy, 2008).ReferencesEdward, N. (2008). Concrete Construction Engineering Handbook. New York: CRC Press.

Term Papers Essays

Term Papers Essays Term Papers Essays Term Papers Essays: How to Reach Success in Writing Writing different assignment papers is rather challenging. But it is an inalienable part of your study. So, neglect such tasks no way! Of course, writing of various term papers, essays, research papers and many other papers takes a lot of time and efforts. But you should not be afraid of them just because of that. If you work at your assignment papers well, you will get a lot of advantages. One should stress that practice in writing is valuable experience. Writing of different term papers, essays and other papers will develop your analytical skills, creative thinking, teach you to express your thoughts and feelings, organize your ideas logically and make conclusions. Why Should You Care? Term papers, essays, reports How can you cope with those numerous assignment papers that you are provided with? How to become successful in the academic writing? Here are some tips that will be helpful for you!Never postpone writing of your assig nment paper. Here you may find 2 because words. Firstly, you cannot write your paper in several hours. You will have to spend some time on gathering and analyzing of information on the topic, developing of your ideas, making of a paper plan and so on. Secondly, you may be provided with other term papers, essays, reports or reaction papers at the same time. So, you are likely to fail to cope with your task in time. Begin your writing with the thorough study of a topic. It is quite obvious that you cannot discuss a paper topic if you have no idea about it. While studying put down all information that may be useful in your writing: different quotations, some names, dates and other precise data. Write down all the ideas that will come to your mind when you prepare for writing. That concerns different kinds of essays especially as the essay papers term suggests applying of your creative skills. But it is obvious that no one can generate all the ideas at once. Make an out line of your assignment paper. That will help you organize your writing. It will be much easier for you if you split your writing into several parts (separate points of your paper) and then discuss each of them consequently. Always check your work. You may make some mistakes while writing. Re-reading of your paper will help avoid them. But pay attention: never check your paper on finishing writing. You should make a break and let your brain have a rest. So, if you keep in mind these pieces of advice, no term papers, essays, reports or any other assignment papers will possess any difficulties for you.

Operationalisation of management and leadership development into Essay

Operationalisation of management and leadership development into practice - Essay Example Leadership and management are the two most confused terms in the corporate world, with both used interchangeably in the corporate parlance. One is thought to be the replacement of the other. Although, management or managers and leaders are two different spheres in an organisational environment, at many places both of them overlap each other. So, we will look at the various aspects of leadership and management with respect to the company GE (General Electric) and see how the two integrate while maintaining the disparity to make this organisation number one enterprise and importantly the best training or developmental ‘school’ for future leaders and managers. To discuss, the management and leadership development, the paper will first critically discuss the current literature on leadership development, focusing on the two leadership developmental processes, leadership training (Flowers 2004) and leadership development programs. Then the paper will delve into pros and cons o f each process to judge whether both the leadership development processes can work effectively with specific emphasis on GE. In recent years the importance of leadership in the organisation has become an area of principle interest. Leadership has been noted to impact corporate culture (Ruchlin 2004), employee commitment and response (Chiok 2001) and the overall performance of the organisation (Peterson, Smith, and Martorana 2003). A precursory overview of the current literature on leadership in the organisation suggests that there are currently two different programs that are utilized for improving the outcomes of leadership: leadership training (Flowers 2004) and leadership development programs (Pernick 2001). While each type of program appears to have the same intent in terms of optimizing leader efficiency, both types of programs are different with each having pros and cons. With the realization that optimizing leadership in the organisation is such an important, there is a

Evidence Based Medicine Essay Example | Topics and Well Written Essays - 4000 words

Evidence Based Medicine - Essay Example They point out that the journals have a scholarly rather than practical approach to solving clinical matters at hand, (Department of Medical Sociology, 1998). With the aim of exploring the barriers that GPs face in the implementation of EBM in routine clinical work and identifying possible strategies in its integration in daily work; studies have been carried out to explore this phenomenon in various parts of the world. One such study was carried out by Kenneth S Yew (MD) and Alfred Reid (MA) from the Uniformed Services University and The University of North Carolina respectively, (Physicians for the twenty-first century, 1984). They held focus group discussions with 10 General Practitioners (GPs) in public and private practice in the randomly selected from Charlotte and its environs. The aim was to find out the long term effects of teaching Critical Appraisal and Evidence Based Medicine on practicing physicians. Their goal was to explore ways in which the long-term outcomes of an integrated CA/EMB curriculum could be evaluated using a qualitative analysis of self-reported use of the two skills in everyday medical practice. Their secondary goal was to find out barriers to CA/EMB application. Reinhold Wentz has estimated that 50,000 physicians, students and health care workers receive training each year, Wentz R. (2001). P Participants mentioned that they had found the approach they used in residency was still helpful to them in situations that they faced as full time GPs, but only in circumstances that allowed them to search and reflect. However, where they immediately had patients to deal with, they preferred to rely on their own intuition and experience. A good number of them expressed guilt that they were not applying the EBM methods even though they were fully aware of how useful these were. Consequently, when it came to the question of barriers, almost all those interviewed were unanimous that time was the main culprit. Some pointed out that where they had to choose between attending to patients and making references, they often found themselves opting for the former. About 30% of the respondents said that they applied the EBM methods regularly but not when resolving an immediate clinical question. Conversely, all the participants were also unanimous on the importance of attending CME courses and as a matter of fact they did attend them. They were sure that they valued keeping up to date as it gave them immense satisfaction. 2% of the participants identified CME as their primary self-learning method. All reported that they regularly read journals while 5% read their specialty society journal regularly. About half also identified teaching and questions arising from patients as their main incentive for learning. Apart from luck of time, the participants also mentioned that the nature of their work kept them constantly under pressure to produce clinically. The majority expressed frustration at this constant pressure to perform, a common sentiment among GPs. Barnett SH et al (2000). Unfortunately, none of them associated performing in their duties with applying EBM since they mostly regarded this as a drawback on quick efficiency. Yet they all felt that they could do their work muc h better if they found the space in their punishing schedules to make references a little more and keep up to date. They figured

Crime and Punishment Analysis Essay Example for Free

Crime and Punishment Analysis Essay Raskolnikov’s redemption is an essential element to the story. His interaction with Profiry is a catalyst for this change. Additionally, the psychological concepts and techniques used by the investigator are crucial aspects of the narrative. In fact, his entire investigation involves the use of psychology to lure out the murderer in what Raskolnikov refers to as a â€Å"cat and mouse game. † Though Raskolnikov considers hi an adversary, his admiration for Porfiry’s intelligence and the good use to which he puts it are critical in redeeming certain aspects of his character. Porfiry Petrovitch is an intelligent young man who works for the betterment of his country. He is greatly devoted to Russia and believes his nation has a bright future. He sees Raskolnikov as a bright young man who can contribute to Russia. Through the story Petrovitch comes to realize that Raskolnikov has fallen under the influence of radical new ideas. He is clearly not a common policeman; otherwise he would have arrested the young man much earlier in the novel. Indeed, Petrovitch’s advanced knowledge of psychological methods makes him come across as an open-minded intellectual. He reads the article Raskolnikov had written about crime. He brings this up in their first encounter and Raskolnikov provides details on his ubbermensch theory. Porfiry concludes that the young student must have included himself in the theory, as he was the one who spread the new idea. He also uses other tactics, such as asking whether Raskolnikov noticed two painters at Ivanova’s apartment. This is an attempt to trap Raskolnikov, who realizes it because there were no painters on site until the day of the murder. However these clever mind games and exchanges provide the novel with a rich, compelling interaction. Raskolnikov recognized Porify’s intelligence, and fears him as an antagonist. The investigator however looks at his suspect differently. Soon Petrovitch’s aim is to show Raskolnikov the error of his theory; that his ideas cannot serve humanity unless they are executed by humane people. Thus a person must employ both humanity and intellect simultaneously in order for their ideas to improve society. By discovering the inaccuracy of his theory, Raskolnikov can begin to accept blame and punishment for his actions. Through suffering for his actions, Raskolnikov can begin his ehabilitation and progress towards becoming the valued addition to society that Petrovitch thinks he can be. Petrovitch believes that he can rehabilitate Raskolnikov into someone who can serve Russia in a useful way. This is exemplified by the final interview, in which he gives Raskolnikov additional time to confess to the crime and thereby reduce his level of punishment. Throughout their exchanges, Petrovitch pushes the main character to do the right thing by appealing to his intellect. His influence on Raskolnikov helps the young man to accept responsibility for his actions and move towards rebuilding his life.

All Quiet On The Western Front the Novel :: Erich Maria Remarque

Kantorek would say We stood on the threshold of life And so it would seem We had as yet taken no root The war swept us away For the others, the older men, It is but an interruption, they are able to think beyond it We, however, have been gripped by it And do not know what the end may be We know only That in some strange and melancholy way We have become a wasteland What does war do to a man? It destroys his inner being; it crushes hope; it kills him. Experiencing battle leaves only the flesh of a man, for he no longer has a personality; it leaves a wasteland where a vast field of humanity once was. Through the main character, Paul Baumer, the reader experiences the hardships and consequences of war. During the course of the war, Paul reflects on how the young men involved in the war have no future left for them, they've become a "lost generation." Paul feels that his generation has "become a wasteland" because the war has made him into a thoughtless animal, because he knew nothing before the war, and because the war has shown the cheapness of human life. Throughout the novel, Paul must face dangerous tasks. For example, in chapter nine Paul crawls through No Man's Land to gather information about enemy forces. While in No Man's Land, the enemy begins to bombard the Germans. Paul, fearing death, hides in an old shell crater and pretends to be dead. While feigning death, an enemy soldier enters the crater. Paul quickly reacts and strike at the enemy with his dagger, fatally wounding the soldier. In a later chapter, Paul explains why he reacted so quickly. War has turned all the soldiers into "unthinking animals in order to give us the weapon of instinct." This primal instinct is one of survival; it is the only thing that matters during war. It allows the soldiers to remain calm in battle, it allows them to escape solitude, and aids them in survival. "As in a polar expedition, every expression of life must serve only the preservation of existence, and is absolutely focused on that;" Paul and the other soldiers do only what is necessary to ensure their own survival. This affects each soldier when the war is finished. When a soldier returns back to his home after the war, he is unable to escape his primitive feelings of survival.

Learning & process Essay

Learning is a never ending process. When a person graduates from primary or tertiary education, he or she should never be contented with the knowledge that he or she has acquired. Instead, there should always be a sense of longing, thriving, and enthusiasm for more knowledge. An adult is just equally capable as a person in his prime years to learn and acquire knowledge. One should not consider his age as an obstacle to nurture and nourish his brain with more information that are yet to be acquired. A person should never be contented with whatever little knowledge he has. An adult who enters graduate school has more advantages than disadvantages. An adult would have more experiences in life and in living compared with others, and this would enable the former to connect his experiences with his education. In other words, there would be a more realistic approach to learning. Often, people who enter graduate school with little experience from their jobs would tend to be more idealistic with their views about the theories presented in class. The decision of an adult to enter into graduate school to obtain a master’s degree falls in between the life stages of Transcending and Life Calling. These stages talks about a person’s journey in life wherein he has already mastered his craft and already knows his strengths and weaknesses. As such, he would now use this knowledge to achieve his goal in life. Thereafter, this person may now realize his purpose and this is associated with his life calling. The reason for living of the person becomes clear, and he is now ready to make radical steps for the realization of his goal. The decision to enter into graduate school is not easy. But, a person who has a clear idea of what he wants in life would not think twice about making this decision. The person would view graduate school as a means, a tool to enable him to achieve his goal to make him successful. Resources: Manifest Your Potential. 2004-2005. The Eight Stages of Life. Retrieved from http://www. manifestyourpotential. com/en/lifeskills/lifestages/eight_stages. htm

Adventures of Huckleberry Finn †Synthesis Essay Essay

Great literature has always run into great controversy, such as classics like The Catcher and the Rye by J. D. Salinger, The Grapes of Wrath by John Steinbeck, and of course The Adventures of Huckleberry Finn by Mark Twain. The Adventures of Huckleberry Finn is of the antics of a 13-year-old Huck, and adult runaway slave. This piece of writing is found to be a classic and a standard for American literature; although recent debate on Twain’s racist language and stereotypical view on African Americans is questioned as appropriate for public education. Mark Twain’s novel, The Adventures of Huckleberry Finn should be taught in public schools, because the story should not be thought of as demeaning to blacks, or that Jim is considered a stereotype of black culture, but merely the characterization is being honest to the story and its time period. In her article â€Å"Huck Finn: Born to Trouble† Katherine Schulten states that parents had additional worries, that Jim would never seem like a true hero to African American children because he does not resist thralldom. Read more:  How to write a good introduction for a synthesis essay. Mark Twain did not want Jim to be some tough guy, who went against the ways of society, who resisted slavery ; does that make the story bad? No it does not, Twain wrote Jim as he was because that is what he was presented with during the time of slavery. Forrest Robinson agrees that Jim’s characterization is profoundly true to the realities of his experience in the novel; but it is culturally true as well in the apparent inconsistency that it has seemed, in the eyes of the audience, to betray. (â€Å"The Characterization of Jim in Huckleberry Finn†). The reality is not many slaves rebelled against white suppression, but there were slaves who escaped from the grips of slavery as Jim did. Charles E. Wilson Jr. author of Race and Racism In Literature notes that Jim’s role in this book is presented from the perspective of a 13-year-old boy. So while Jim may appear to be an object instead of a man, it is rather Huck’s bias and naive version of Jim that we see. In Huck’s viewpoint Jim is a â€Å"nigger†, and a slave, and in such manner, he should remain inferior to Huck, even though ironically, Huck treats Jim altruistically. Throughout the novel Jim presents his wisdom, but Huck considers it a site of black inferiority. In almost every instance of Twain’s verbal irony, Jim emerges the intellectual victor. Although Jim is foreseen as a weak, dumb, stereotypical black because it is in the narrative of a â€Å"civilized† white boy. This story is truly one of the great American novels of all time, nothing like it had ever been done, and nothing like it has ever been done since. As Shelley Fishkin points out Huckleberry Finn allowed a different kind of writing to happen: a clean, crisp, nonsense, earthy, vernacular kind of writing that jumped off printed page with unprecedented immediacy and energy; it was a book that talked. (â€Å" Huck’s Black Voice†) Twain’s writing was every bit of unusual, he did not write to comfort the human minds, or to pamper the society and mask the human faults. This novel has enticing freedom, not just in the story, but as a novel itself; no book had ever tried to break free from the hackneyed writing of the time. â€Å"As I knew from my first encounter with the book on high school, critics had long viewed Huckleberry Finn as a declaration of independence from the genteel English novel tradition. † (â€Å"Huck’s Black Voice†) Great literature has always run into great controversy. Twain wrote The Adventures of Huckleberry Finn from what he was provided with in his society, he did not give any false illusions of what was going on; he simply wrote an adventure of escape through the eyes of a young 13-year-old white boy. Does it have racism? Yes–but it also has self-discovery, chivalry, friendship, and vibrant adventure. Public education should continue in the use of this great novel because of what it provides. Just from this one topic of the book, it has stirred much discussion and debate. Imagine, all this interaction, involvement, and opinion in the classroom from kids of many backgrounds. When it comes down to it, this book makes the reader think of what really matters in life, and that anyone can make a difference. Works Cited Wilson, Charles E. Race and Racism in Literature. Westport, Conn. : Greenwood, 2005. Print.

Free Essays on Can You Deny Your Child Medical Care For Religious Reasons

Religion is a part of many Americans lives. It is a part of many people across the world’s lives, but it is a bigger part of some people’s lives then others. Religion is something that people believe in. It is a set of rules that they chose to live by because they believe that God gave them these rules. Some people’s religions guide there lives more so then others. Certain religions put restrictions on its followers, and those restrictions can include types of medical treatments they can and can’t receive. The question to be discussed in this paper is whether or not parents that are followers of these religions have the right to deny treatment to their children as well. Some say that religious freedom is what this country was founded on, and that by telling people that they can’t chose to not give their children medical attention, is taking away there right to that freedom. Others say that children don’t chose to be a part of these religions and that they aren’t making this decision consciously, or on their own accord, so they are in need of representation of their rights from authorities. There are two well known religions that avoid conventional medical treatment the Jehovah Witnesses and the Christian Scientists, there are many other smaller sects that carry similar beliefs and they are as follows: The Body â€Å"The Body of Christ†, Bible Readers Fellowship, Church of the First Born, End Time Ministries, Faith Assembly, Full Gospel Deliverance Church, Faith Tabernacle Congregation, Christ Church, Grace Baptist Church, and Home in Zion Ministries, there are probably others but these are the ones currently recognized according to Robinson (2002). The one thing that all these religions have in common is that somewhere in their translation of the bible they believe that God has told them not to allow for any other form of medical treatment other than prayer, and occasionally the use of oils or everyday household products... Free Essays on Can You Deny Your Child Medical Care For Religious Reasons Free Essays on Can You Deny Your Child Medical Care For Religious Reasons Religion is a part of many Americans lives. It is a part of many people across the world’s lives, but it is a bigger part of some people’s lives then others. Religion is something that people believe in. It is a set of rules that they chose to live by because they believe that God gave them these rules. Some people’s religions guide there lives more so then others. Certain religions put restrictions on its followers, and those restrictions can include types of medical treatments they can and can’t receive. The question to be discussed in this paper is whether or not parents that are followers of these religions have the right to deny treatment to their children as well. Some say that religious freedom is what this country was founded on, and that by telling people that they can’t chose to not give their children medical attention, is taking away there right to that freedom. Others say that children don’t chose to be a part of these religions and that they aren’t making this decision consciously, or on their own accord, so they are in need of representation of their rights from authorities. There are two well known religions that avoid conventional medical treatment the Jehovah Witnesses and the Christian Scientists, there are many other smaller sects that carry similar beliefs and they are as follows: The Body â€Å"The Body of Christ†, Bible Readers Fellowship, Church of the First Born, End Time Ministries, Faith Assembly, Full Gospel Deliverance Church, Faith Tabernacle Congregation, Christ Church, Grace Baptist Church, and Home in Zion Ministries, there are probably others but these are the ones currently recognized according to Robinson (2002). The one thing that all these religions have in common is that somewhere in their translation of the bible they believe that God has told them not to allow for any other form of medical treatment other than prayer, and occasionally the use of oils or everyday household products...

The 1932 March of the Veterans Bonus Army

The 1932 March of the Veterans Bonus Army The Bonus Army was the name applied a group over 17,000 U.S. World War I veterans who marched on Washington, D.C. during the summer of 1932 demanding immediate cash payment of the service bonuses promised to them by Congress eight years earlier. Dubbed the â€Å"Bonus Army† and â€Å"Bonus Marchers† by the press, the group officially called itself the â€Å"Bonus Expeditionary Force† to mimic the name of World War Is American Expeditionary Forces. Fast Facts: March of the Veterans Bonus Army Short Description: 17,000 World War I veterans occupy Washington, D.C., and march on the U.S. Capitol to demand payment of promised military service bonuses.Key Participants:- President of the United States Herbert Hoover- U.S. Army General Douglas MacArthur- U.S. Army Major George S. Patton- U.S. Secretary of War Patrick J. Hurley- District of Columbia Police Department- At least 17,000 U.S, WWI veterans and 45,000 supporting protestersLocation: In and around Washington, D.C., and the United States Capitol groundsStart Date: May 1932End Date: July 29, 1932Other Significant Dates:- June 17, 1932: U.S. Senate defeated a bill that would have advanced the date of payment of bonuses to the veterans. Two veterans and two D.C. police officers die in the ensuing protest.- July 29, 1932:   On the order of President Hoover, through Sec. of War Hurley, U.S. Army troops commanded by Maj. George S. Patton attack the veterans forcing them from their encampments and effectively ending the crisis . A total of 55 veterans were injured and another 135 were arrested.Fallout:- President Hoover was defeated by Franklin D. Roosevelt in the 1932 presidential election.- Roosevelt immediately reserved jobs for 25,000 WWI veterans in his New Deal program.- In January 1936, WWI veterans were paid over $2 billion in promised combat bonuses. Why the Bonus Army Marched Most of the veterans who marched on the Capitol in 1932 had been out of work since the Great Depression began in 1929. They needed money, and the World War Adjusted Compensation Act of 1924 had promised to give them some, but not until 1945 a full 27 years after the end of the war they had fought in. The World War Adjusted Compensation Act, passed by Congress as sort of a 20-year insurance policy, awarded all qualified veterans a redeemable â€Å"Adjusted Service Certificate† worth an amount equal to 125% of his wartime service credit. Each veteran was to be paid $1.25 for each day they had served overseas and $1.00 for each day they served in the United States during the war. The catch was that the veterans were not allowed to redeem the certificates until their individual birthdays in 1945. On May 15, 1924, President Calvin Coolidge had, in fact, vetoed the bill providing for the bonuses stating, â€Å"Patriotism, bought and paid for, is not patriotism.† Congress, however, overrode his veto a few days later. While the veterans might have been happy to wait for their bonuses when the Adjusted Compensation Act passed in 1924, the Great Depression came along five years later and by 1932 they had immediate needs for the money, like feeding themselves and their families. The Bonus Army Veterans Occupy D.C. The Bonus March actually began in May 1932 as some 15,000 veterans assembled in makeshift camps scattered around Washington, D.C. where they planned to demand and wait for the immediate payment of their bonuses.   The first and largest of the veterans’ camps, dubbed â€Å"Hooverville,† in as a backhanded tribute to President Herbert Hoover, was located on Anacostia Flats, a swampy bog directly across the Anacostia River from the Capitol Building and the White House. Hooverville housed about 10,000 veterans and their families in ramshackle shelters built from old lumber, packing boxes, and scrapped tin  from a nearby junk pile. Including the veterans, their families, and other supporters, the crowd of protesters eventually grew to nearly 45,000 people. Veterans, along with the assistance of the D.C. Police, maintained order in the camps, built military-style sanitation facilities, and held orderly daily protest parades. The D.C. Police Attack the Veterans On June 15, 1932, the US House of Representatives passed the Wright Patman Bonus Bill to move up the payment date of the veterans’ bonuses. However, the Senate defeated the bill on June 17. In protest to the Senate’s action, the Bonus Army veterans marched down Pennsylvania Avenue to the Capitol Building. The D.C. police reacted violently, resulting in the deaths of two veterans and two police officers. The U.S. Army Attacks the Veterans On the morning of July 28, 1932, President Hoover, in his capacity as Commander in Chief of the military, ordered his Secretary of War Patrick J. Hurley to clear the Bonus Army camps and disperse the protesters. At 4:45 p.m., U.S. Army infantry and cavalry regiments under the command of General Douglas MacArthur, supported by six M1917 light tanks commanded by Maj. George S. Patton, assembled on Pennsylvania Avenue to carry out President Hoover’s orders.   With sabers, fixed bayonets, tear gas, and a mounted machine gun, the infantry and the cavalry charged the veterans, forcibly evicting them and their families from the smaller camps on the Capitol Building side of the Anacostia River. When the veterans retreated back across the river to the Hooverville camp, President Hoover ordered the troops to stand down until the next day. MacArthur, however, claiming the Bonus Marchers were attempting to overthrow the U.S. government, ignored Hoover’s order and immediately launched a second charge. By the end of the day, 55 veterans had been injured and 135 arrested. The Aftermath of the Bonus Army Protest In the 1932 presidential election, Franklin D. Roosevelt defeated Hoover by a landslide vote. While Hoover’s militaristic treatment of the Bonus Army veterans may have contributed to his defeat, Roosevelt had also opposed the veterans’ demands during the 1932 campaign. However, when the veterans held a similar protest in May 1933, he provided them with meals and a secure campsite. To address the veterans’ need for jobs, Roosevelt issued an executive order allowing 25,000 veterans to work in the New Deal program’s Civilian Conservation Corps (CCC) without meeting the CCC’s age and marital status requirements. On January 22, 1936, both houses of Congress passed the Adjusted Compensation Payment Act in 1936, appropriating $2 billion for the immediate payment of all World War I veterans’ bonuses. On January 27, President Roosevelt vetoed the bill, but Congress immediately voted to override the veto. Almost four years after they had been driven from Washington by Gen. MacArthur, the Bonus Army veterans finally prevailed. Ultimately, the events of the Bonus Army veterans’ march on Washington contributed to the enactment in 1944 of the GI Bill, which has since assisted thousands of veterans make the often difficult transition to civilian life and in some small way pay back the debt owed to those who risk their lives for their country.

The Encryption of Information Essay Example | Topics and Well Written Essays - 750 words

The Encryption of Information - Essay Example Accordingly, the potential of encryption is being recognized as an essential element in fostering electronic commerce, worldwide.   In this direction, European Union has referred to this subject in their recent publication, in which the digital signatures and encryption have been identified as the important applications of cryptography (Holland, Cyberspace-law)   The process of encryption involves the conversion of the relevant data into a particular code, while a specific algorithm and key would be required to interpret the given code or cipher. While this process ensures the security of data, in case of any theft of the computer or device storing the data, its security is also ensured even when the data is tapped by an unauthorized third party, during its transmission over a network.   Therefore, data can be encrypted, while it is placed in a stored compartment, like a computer folder. Similarly, the encryption ensures that data is safe when it is being transmitted from one device to another, through a network. While the earlier would be a â€Å"Storage encryption†, the later is named as a â€Å"transmission encryption†Ã¢â‚¬ ¦.(Encryption at the University of California, 2006)   Although data security is of prime importance to the American federal policymakers, reports suggest that the governmental agencies have not achieved much in this regard. As per a report from Nebraska Bankers Association, dated August 5, 2008, the U.S. House committee on homeland security chairman.

The Reasons for the Civil War in China Between the KMT and CCP Essay

The Reasons for the Civil War in China Between the KMT and CCP (1945-49) and why the CCP Won - Essay Example Although the Communists got permission to be part of the KMT in small numbers, Chiang started a purge of communists since he abhorred the Soviet interfering in Chinese political affairs. This eventually led to the Chinese civil war (Eastman 11). Following the collapse of the Qing Dynasty in 1911, which was the final ruling Chinese dynasty, China fell into the control of a number of significant, as well as lesser warlords within the era of the Warlords. Therefore in order to trounce these warlords, who succeeded in seizing control of the greater part of Northern China, it was necessary for the anti-monarchist, together with the national unificationist Kuomintang party, along with Sun Yat-sen, who was its leader, to seek the assistance of foreign powers. The efforts of Sun Yat-sen in obtaining assistance from the Western democracies bore no fruits these led to him seeking help from the Soviet Union in 1921. In favour of political convenience, the Soviet leadership instigated a dual pol icy for supporting for both Sun, as well as the newly founded Communist Party of China that subsequently instituted the People's Republic of China. This resulted in the struggle for power within China between the KMT, along with the CPC (Eastman 25). ... in the reorganization, in addition to the consolidation of, the KMT alongside the Communist Party of Soviet Union, leading to the CPC uniting the KMT, thereby developing into the First United Front. This is the same year that saw Sun Yat-sen sending Chiang Kai-shek, who happened to be one of his lieutenants to Moscow for some months' military, as well as political study. By 1924, Chiang got promoted to head Whampoa Military Academy, then later rising to fame as Sun's successor, thereby heading the KMT. The Soviets offered the majority of the studying items, organization, in addition to the equipment comprising, of munitions for the academy. Apart from that, the Soviets also offered education in various methods for mass mobilization. This assisted Sun Yat-sen in raising a number of devoted troops, with the intention of defeating the warlords militarily. On the other hand, CPC members also got the opportunity of joining the academy with the majority of them becoming instructors. Howeve r, the communist members got the opportunity of uniting the KMT on the basis of an individual. At that time, the CPC was still exceedingly small, having only 300 members in 1922, and in 19925, only 1,500 members while the KMT had 50,000 members in 1923 (Eastman 54). The split of KMT and CPC In the beginning of 1927, there was rivalry between KMT and CPC leading to a split within the revolutionary positions. The CPC, along with left wing of KMTmade a decision of moving the KMT government’s seat to Wuhan from Guangzhou, where the influence of communist was strong. However, Chiang, together with Li Zongren, whose armies conquered warlord Sun Chuanfang, progressed eastward towards Jiangxi. As a result of the leftists rebuffing Chiang's demand, Chiang condemned the leftists for going against

Architecture - Avant Garde Architectural Theory Essay

Architecture - Avant Garde Architectural Theory - Essay Example In the beginning of 1922, the Viennese Hungarian Activists were gaining victory. After banishing from Hungary they got together in Vienna. Earlier this year, some of them started to get cut off from Kassak and Ma, making their own groups. In impact of Russian Avant garde was the main cause for the Hungarian Activists to break from Dada and join International Constructivism. The Activist "artists and writers" were the main groups forming the Hungarian Avant garde during that time (Botar, 1993). Brutalism was a movement in architecture which flourished in the 1960s and 1970s. Pioneered in continental Europe by Le Corbusier, its main protagonists in Britain were the husband and wife team of Peter and Alison Smithson. The Smithsons were determined to preserve the best aspects of the heroic Modernism of Ludwig Mies Van Der Rohe and other early pioneers, and to save British Modernism from what they considered creeping whimsies. The term itself (often credited to the critic Reynar Banham) is perhaps unfortunate- suggesting as it does a type of building which is ugly and unfriendly, and its association with much of Britain's welfare state architecture has not helped the movement's reputation, at least in the eyes of the public (The New Architecture, 1955). Also in the research paper, one building and one piece of text will be analysed. The building to be analysed is the Hunstanton school, by Alison and Peter Smithson in Norfolk, Britain and the piece of text to be analysed is "Banham, Peter Rayner 1955-'The New Brutalism' from architecture review." After the Second World War, British Modernists were increasingly sought after by the authorities who wanted to rebuild a physically shattered country and enact social change through the construction of a cradle-to-grave welfare state. But the architecture of the early welfare state avoided the stringent Modernism advocated by the pre-war pioneers in CIAM, opting instead to ape the gentle style of Sweden's long established social architecture. The apotheosis of this 'humanist' Modernism came in 1951, with the Festival of Britain, centred on the South Bank in London. (The New Architecture, 1955) For Peter and Alison Smithson, modernism was not just that. They demanded a return to a more rigid, formal architecture and put their ideas to work with their Secondary School in Hunstanton, Norfolk, completed in 1954. At Hunstanton, the Smithsons made a virtue of the construction process of the building: structural and service elements were left exposed and the austere steel and glass frame gave the building a skeletal appearance. This "truth to materials" approach was anti-aesthetic, but, the Smithsons believed, more honest and true to Modernism's basic principles. Reynar Banham dubbed the school 'the New Brutalism', a movement which aimed, in his words, to "make the whole conception of the building plain and comprehensible. No mystery, no romanticism, no obscurities about function and circulation." In France, Le Corbusier was also experimenting with new ways of using the Modernists' favourite material, concrete. His "breton brut" (literally, "raw concrete") technique characterised his Unite d'Habitation in Marseilles: a giant housing block with shops and other

A Blood Brain Pharmacokinetic Model

A Blood Brain Pharmacokinetic Model Pharmacokinetics, an emerging field in BioPhysics and chemistry is the study of the time variation of drug and metabolite levels in various tissues and fluids of the body. Compartment models are used to interpret data. In our problem, we consider a simple blood-brain compartment model as shown in the figure below: k21 Input d(t) k12 K where, Compartment 1 = Blood Compartment 2 = Brain This model is made such that it can aid to help estimate dosage strengths of an orally administered antidepressant drug. The rate of movement of drug from compartment i to compartment j is denoted by the rate constant kji and the rate at which the drug is removed from the blood is represented by the rate constant K. A pharmaceutical company must deal with many factors like dosage strengths that will aid a physician in determining a patients dosage in order to maintain the right concentration levels and also minimizing irritation and other side effects (Brannan 208). If we assume that the drug is rapidly absorbed into the blood stream after it is introduced into the stomach, a mathematical representation of the dosage will be of a periodic square wave given as follows: Based on our model and the equations we can solve the problems: 1. If we let xj(t) be the amount of drug in milligrams in compartment j, j =1,2. The mass balance law states: (i) Using the mass balance law and the figure, we find: System in Blood compartment: System in Brain compartment: From (i) and the above equations, we can find the following: (ii) The systems above are the rates of drug over time in the compartments. 2. If we let ci(t) denote the concentration of the drug and Vi denote the apparent volume of distribution in compartment i, we can use the relation ci = xi/Vi in the equations of system (ii) to obtain: (iii) Dividing the above systems by V1 and V2 respectively, we get : 3. Assuming x1(0) =0 and x2(0) =0, and the various parameters listed below: k21 k12 K V1 V2 Tb 0.29/h 0.31/h 0.16/h 6L 0.25L 1h and with the numerical simulation program Maple , we can perform simulations of the system with given parameters to recommend two different encapsulated dosage strengths A=RTb. => Guidelines to use for recommendation of drug dosage: 1) Target concentration level in the brain should be kept as close as possible between levels 10 mg/L and 30 mg/L and concentration fluctuation should not exceed 25% of the average of the steady-state response. 2) Lower frequency of administration (once every 24 hours or once every 12 hours is best). Once every 9.5 hours is unacceptable and multiple doses are acceptable (i.e. taking two capsules every 4 hours) Analysis: Drug usage of more than 4 times per day is unacceptable which makes maximum allowable dose to be 3, making 3 doses at 8 hours interval per day the best choice. We can then simulate from Tp = 8 to Tp = 12, 16 and 24. From the numerical simulations obtained from Maple, we obtain the following data: Tp(h) R (mg/h) Steady-state variance Comments 8 4 9.04 mg/L to 12.5 mg/L Below effective therapeutic concentration 8 5 11.7 mg/L to 15.5 mg/L 8 6 14.4 mg/L to 19.2 mg/L 8 8 19.2 mg/L to 25.3 mg/L 8 9 21.1 mg/L to 27.9 mg/L 8 10 23.2 mg/L to 31.2 mg/L Above maximum therapeutic concentration 12 5 10.9 mg/L to 6.5 mg/L Below minimum therapeutic concentration 12 6 8.6 mg/L to 14.1 mg/L Below minimum therapeutic concentration 12 7 8.32 mg/L to 15.1 mg/L Below minimum therapeutic concentration 12 8 10.6 mg/L to 18.3 mg/L 12 10 13.2 mg/L to 22.8 mg/L 12 13 17.9 mg/L to 30 mg/L 16 10 9.11 mg/L to 19.5 mg/L Sharp fluctuations; Below minimum therapeutic concentration 16 12 10.7 mg/L to 23.5 mg/L Sharp fluctuations. 16 13 11.5 mg/L to 25.4 mg/L Sharp fluctuations. 16 14 12.5 mg/L to 27.3 mg/L Sharp fluctuations. 16 16 14.3mg/L 31.4mg/L Sharp fluctuations; Above maximum therapeutic concentration 24 15 6.19mg/L 24mg/L Sharp fluctuations; Below minimum therapeutic concentration 24 20 8.52mg/L 32mg/L Sharp fluctuations; Above maximum therapeutic concentration Obtained corresponding Graphs from Maple and their respective Tp and R values are listed below: Tp = 8, R = 4 Tp = 8, R = 5 Tp = 8, R = 6 Tp = 8, R = 8 Tp = 8, R = 9 Tp = 8, R = 10 Tp = 12, R = 6 Tp = 12, R = 8 Tp = 12, R = 10 Tp = 12, R = 12 Tp = 12, R = 13 Tp=16, R=10 Tp=16, R=12 Tp=16, R=13 Tp=16, R=14 Tp=16, R=16 Tp=24, R=15 Tp=24, R=20 Some Comments: When Tp= 8 and R = 4, the recommended dosage is below minimum therapeutic concentration range. When Tp= 8 and R = 10 , the recommended dosage is above maximum therapeutic concentration range. When Tp= 8 and R = 5 to 7, the recommended dosage is below effective therapeutic concentration range. When Tp= 8 and R = 4, the recommended dosage is below therapeutic concentration range. When Tp= 12 and R = 5 to 7, the recommended dosage is below minimum therapeutic concentration range. When Tp= 16 and R = 12 to 14, sharp fluctuation is seen. When Tp= 24 and R = 20, sharp fluctuation is seen and the recommended dosage is below therapeutic concentration range. =>Calculation and Analysis of dosage strength A Now we can calculate the dosage frequency for the remaining dosage frequency intervals of 8 hours and 12 hours: (8 hour interval) (R being from 5 mg/h to 9 mg/h) A = RTb = 5 mg/h x 1h= 5 mg A = RTb = 9 mg/h x 1h= 9 mg (12 hour interval) (R being from 8 mg/h to 13 mg/h) A = RTb = 8 mg/h x 1h = 8 mg A = RTb = 13 mg/h x 1h= 13 mg 4. From the simulation, we can know that it is best to skip the dose than to try to catch up and double the dose and ultimately overdose from the figures illustrated. If we assume the patient is at a 12 hour interval dose frequency, and R being 10mg/h, the following scenarios can be simulated:   Scenario: missed a dosage and skipped     Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Scenario: missing a dosage catching up Analysis: From the scenarios simulations above, we can have a clear picture of what will go through the patients drug level. In the 1st scenario, where the patient missed a dosage and skipped, the concentration level in the brain of the patient stays within the recommended level. In the 2nd scenario, where the patient tries to catch up, the drug level will cross the recommended level and that also by a lot. Thus, skipping the dose is better than to catch up overdosing the drug level resulting in fatality.   5. Supposing the drug can be packaged in a timed-release form so that Tb = 8 hours and R also adjusted likewise, we get the following data from the Maple: Tp(h) R(mg/h) Steady-state variance Reasons 12 0.75 10.4mg/L 13mg/L 12 1 13.9mg/L 17mg/L 12 1.5 21mg/L 25.5mg/L 12 1.75 24.5mg/L 29.8mg/L 12 2 28.1mg/L 34mg/L Above maximum therapeutic concentration 16 1 9mg/L 14.3mg/L Below minimum therapeutic concentration 16 1.25 11.2mg/L 17.7mg/L 16 1.5 13.6mg/L 21.3mg/L 16 2 18.3mg/L 28.4mg/L 16 2.25 20.5mg/L 31.8mg/L Above maximum therapeutic concentration 16 2.5 22.8mg/L 35.4mg/L Above maximum therapeutic concentration 24 2 8.7mg/L 23.3mg/L Sharp fluctuation 24 2.25 9.86mg/L 25.9mg/L Sharp fluctuation 24 2.5 10.9mg/L 29mg/L Sharp fluctuation T=12, R=0.75 T=12, R=1 T=12, R=1.5 T=12, R=1.75 T=12, R=2 T=16, R=1 T=16, R=1.25 T=16, R=1.5 T=16, R=2 T=16, R=2.25 T=16, R=2.5 T=24, R=2 T=24, R=2.5 Analysis: If the drug can be packaged in a timed release form so that Tb = 8 and R is also adjusted likewise, we perform the simulations for the dosage of interval of a 12 hour frequency. We observe zero sharp fluctuations. Every graph seems to produce the concentration level within the recommended range of 10mg/L to 30mg/L when R is between 0.75 mg/h and 1.75 mg/h. =>Calculation and Analysis of new dosage strength A We can calculate the new strength level of the drugs as: (12 hour frequency interval): A=RTb = 0.75 mg/h * 8h = 6mg   A=RTb = 1.75 mg/h * 8h = 14mg Same analysis can be performed for 16 hour frequency interval. We observe zero sharp fluctuations and every graph produce the concentration level within the recommended range of 10mg/L to 30mg/L; R being in between 1.25mg/h and 2mg/h.   =>Calculation and Analysis of new dosage strength A We can calculate the new strength level of the drugs as:   (16 hour frequency interval): A = RTb=1.25 mg/h * 8h = 10mg    A = RTb=2.00 mg/h * 8h = 16mg Thus, this changes our recommendation. Simulation Program Maple: We used the following code and simulated varying R and P values. g :=t> piecewise(0 DEplot({diff(x(t), t) = (1/6)*g(t)+(1/6)*(.31*.25)*y(t)-x(t)*(.29+.16), diff(y(t), t) = (.29*6)*x(t)/(.25)-.31*y(t)}, [x(t), y(t)], t = 0 .. 40, x = 0 .. .50, y = 0 .. 80, scene = [t, y], [[x(0) = 0, y(0) = 0]], stepsize = .1, color = blue)